Phylogenetics BASICS
Short introduction to phylogenetics
Sequencing Protocols
PANGEA 1: Gall et al
PANGEA 2: Bonsall et al
ABOUT PANGEA
Webinars
Chris Wymant |
Introduction to Phylogenetics |
Christophe Fraser |
How to interpret a viral phylogeny |
Matthew Hall |
Introduction to Phylodynamics |
Brian Foley |
Multiple sequence alignment for HIV |
Brian Foley |
Recombination in HIV |
Steven Kemp |
Introduction to whole genome sequence analysis - part 1 |
Steven Kemp |
Introduction to whole genome sequence analysis - part 2 |
David Bonsall |
Using NGS data to identify HIV drug resistance mutations |
Diego Cuadros |
Geographical models in epidemiology |
Oliver Ratmann |
Are high prevalence fishing communities on Lake Victoria the predominant source of new HIV infections in Rakai, Uganda? |
Nicholas Bbosa |
Using phylogenetics and modeling to understand HIV-1 transmission dynamics in Ugandan fishing communities |
Sarah Fidler |
Results of the HPTN 071 (PopART) HIV UTT trial |
Publications
PANGEA-HIV 2: Phylogenetics And Networks for Generalised Epidemics in Africa.
Abeler-Dörner, L, Grabowski KM, Rambaut A, Pillay D, Fraser C (2019). Curr Opin HIV AIDS 14, 173–180
Ratmann O, Groabowski KM, Hall M, Golubchik T, Wymant C, Abeler-Dörner L, Bonsall D, Hoppe A, Leigh Brown A, de Oliveria T, Gall A, Kellam P, Pillay D, Kagaayi J, Kigozi G, Quinn TC, Wawer MJ, Laeyendecker O, Serwadda D, Gray RH, Fraser C on behalf of the PANGEA consortium and the Rakai Health Sciences Program (2019). Nat Commun 10, 1411
Bbosa N, Ssemwanga D, Nsubuga RN, Salazar-Gonzalez JF, Salazar MG, Nanyonjo M, Kuteesa M, Seeley J, Kiwanuka N, Bagaya BS, Yebra G, Leigh-Brown A, Kaleebu P (2019). Sci Rep 9, 1051
Bonsall D, Golubchik T, de Cesare M,, Limbada M, Kosloff B, MacIntyre-Cockett G, Hall M, Wymant C, Ansari A, Abeler-Dörner L, Schaap, A, Borwn A, Bares E, Piwowar-Manning E, Wilson E, Emel L, Hayes R, Filder S, Ayles H, Bowden R, Fraser C (2018). BioRxiv, 397083
Ethical considerations in global HIV phylogenetic research.
Coltart CEM, Hoppe A, Parker M, Dawson L, Amon JJ, Simwinga M, Geller G, Henderson G, Laeyendecker O, Tucker JD, Eba P, Novitsky V, Vandamme AM, Seeley J, Dallabetta G, Harling G, Grabowski MK, Godfrey-Faussett P, Fraser C, Cohen MS, Pillay D; Ethics in HIV Phylogenetics Working Group (2018). Lancet HIV 5: e656-e666
Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver.
Wymant C, Blanquart F, Golubchik T, Gall A, Bakker M, Bezemer D, Croucher NJ, Hall M, Hillebregt M, Ong SH, Ratmann O, Albert J, Bannert N, Fellay J, Fransen K, Gourlay A, Grabowski MK, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos R, Laeyendecker O, Liitsola K, Meyer L, Porter K, Ristola M, van Sighem A, Berkhout B, Cornelissen M, Kellam P, Reiss P, Fraser C; BEEHIVE Collaboration (2018).
Virus Evol 4, vey007
PHYLOSCANNER: Inferring Transmission from Within- and Between-Host Pathogen Genetic Diversity.
Wymant C, Hall M, Ratmann O, Bonsall D, Golubchik T, de Cesare M, Gall A, Cornelissen M, Fraser C; STOP-HCV Consortium, The Maela Pneumococcal Collaboration, and The BEEHIVE Collaboration (2017). Mol Biol Evol 35, 719-733
Ratmann O, Wymant C, Colijn C, Danaviah S, Essex M, Frost SDW, Gall A, Gaiseitsiwe S, Grabowski M, Gray R, Guindon S, von Haeseler A, Kaleebu P, Kendall M, Kozlov A, Manasa J, Minh BQ, Moyo S, Novitsky V, Nsubuga R, Pillay S, Quinn TC, Serwadda D, Ssemwanga D, Stamatakis A, Trifinopoulos J, Wawer M, Leigh Brown A, de Oliveira T, Kellam P, Pillay D, Fraser C (2017). AIDS Res Hum Retroviruses 33, 1083-1098
Phylogenetic Tools for Generalized HIV-1 Epidemics: Findings from the PANGEA-HIV Methods Comparison.
Ratmann O, Hodcroft EB, Pickles M, Cori A, Hall M, Lycett S, Colijn C, Dearlove B, Didelot X, Frost S, Hossain AS, Joy JB, Kendall M, Kühnert D, Leventhal GE, Liang R, Plazzotta G, Poon AF, Rasmussen DA, Stadler T, Volz E, Weis C, Leigh Brown AJ, Fraser C; PANGEA-HIV Consortium (2017). Mol Biol Evol 34, 185-3203
Yebra G, Hodcroft EB, Ragonnet-Cronin ML, Pillay D, Brown AJ; PANGEA_HIV Consortium; ICONIC Project (2016). Sci Rep 23, 39489
PANGEA-HIV: phylogenetics for generalised epidemics in Africa.
Pillay D, Herbeck J, Cohen MS, de Oliveira T, Fraser C, Ratmann O, Brown AL, Kellam P; PANGEA-HIV Consortium (2015). Lancet Infect Dis 15, 259-6
Universal amplification, next-generation sequencing, and assembly of HIV-1 genomes.
Gall A, Ferns B, Morris C, Watson S, Cotten M, Robinson M, Berry N, Pillay D, Kellam P. (2012)
J Clin Microbiol 50, 3838-44